类视紫红质受体
外观
类视紫红质受体 | |||||||||||
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鑑定 | |||||||||||
標誌 | 7tm_1 | ||||||||||
Pfam | PF00001(旧版) | ||||||||||
Pfam宗系 | GPCR_A(旧版) | ||||||||||
InterPro | IPR000276 | ||||||||||
PROSITE | PDOC00211 | ||||||||||
SCOP | 1f88 / SUPFAM | ||||||||||
OPM家族 | 6 | ||||||||||
OPM蛋白 | 1gzm | ||||||||||
CDD | cd00637 | ||||||||||
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类视紫红质受体,又可译作视紫红质样受体、类视紫质受体(英語:Rhodopsin-like receptors),是一个G蛋白偶联受体蛋白超家族下成员最多的蛋白家族[2],因都具有与视紫红质(视紫质)相似的由七个α螺旋组成的穿膜结构而得名[3][4][5]。
类视紫红质受体下有19个亚家族[6]。
参考文献
[编辑]- ^ Palczewski K, Kumasaka T, Hori T, et al. Crystal structure of rhodopsin: A G protein-coupled receptor. Science. August 2000, 289 (5480): 739–45. Bibcode:2000Sci...289..739P. PMID 10926528. doi:10.1126/science.289.5480.739.
- ^ Attwood TK, Findlay JB. Fingerprinting G-protein-coupled receptors. Protein Eng. 1994, 7 (2): 195–203. PMID 8170923. doi:10.1093/protein/7.2.195.
- ^ Birnbaumer L. G proteins in signal transduction. Annu. Rev. Pharmacol. Toxicol. 1990, 30: 675–705. PMID 2111655. doi:10.1146/annurev.pa.30.040190.003331.
- ^ Gilman AG, Casey PJ. G protein involvement in receptor-effector coupling. J. Biol. Chem. 1988, 263 (6): 2577–2580. PMID 2830256.
- ^ Attwood TK, Findlay JB. Design of a discriminating fingerprint for G-protein-coupled receptors. Protein Eng. 1993, 6 (2): 167–176. PMID 8386361. doi:10.1093/protein/6.2.167.
- ^ Joost P, Methner A. Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome Biol. 2002, 3 (11): research0063.1–0063.16. PMC 133447 . PMID 12429062. doi:10.1186/gb-2002-3-11-research0063.
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