诺孕烯酮

**诺孕烯酮**
臨床資料
商品名（英语：Drug nomenclature）	Ogyline, Planor, Miniplanor
其他名稱	RU-2010; A-301; 17α-Ethynyltrienolone; 17α-Ethynyltrenbolone; Δ9,11-Norethisterone; 17α-Ethynylestra-4,9,11-trien-17β-ol-3-one
给药途径	口服给药
藥物類別（英语：Drug class）	Progestogen; Progestin; Androgen; Anabolic steroid
ATC碼	G03AC07 (WHO) ;
识别信息
	IUPAC命名法 (8S,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; ;
CAS号	848-21-5
PubChem CID	13313;
ChemSpider	12749 ;
UNII	89386PYU9O;
KEGG	D07220 ;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID30878491 ;
ECHA InfoCard	100.011.544
化学信息
化学式	C20H22O2
摩尔质量	294.39 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES O=C4\C=C3/C(=C2/C=C\[C@]1([C@@H](CC[C@]1(C#C)O)[C@@H]2CC3)C)CC4;
	InChI InChI=1S/C20H22O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,8,10,12,17-18,22H,4-7,9,11H2,2H3/t17-,18+,19+,20+/m1/s1 ; Key:GVDMJXQHPUYPHP-FYQPLNBISA-N ;

诺孕烯酮（英語：Norgestrienone，或译为去甲孕三烯酮，商品名: Ogyline, Planor, Miniplanor 等）是一种甾体药物，分子式C₂₀H₂₂O₂，由法国药企Roussel Uclaf开发，可用作复合口服避孕药，常与炔雌醇联用^[1]^[2]^[3]^[4]^[5]。

参考文献[编辑]

^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 887–. ISBN 978-1-4757-2085-3.
^ Morton IK, Hall JM. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 202– [2023-02-02]. ISBN 978-94-011-4439-1. （原始内容存档于2023-01-10）.
^ Diaz S, Pavez M, Quinteros E, Diaz J, Robertson DN, Croxatto HB. Clinical trial with subdermal implants containing norgestrienone. Contraception. October 1978, 18 (4): 429–40. PMID 720075. doi:10.1016/0010-7824(78)90027-6.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000: 751–. ISBN 978-3-88763-075-1.
^ Sweetman, Sean C. (编). Sex hormones and their modulators. Martindale: The Complete Drug Reference 36th. London: Pharmaceutical Press. 2009: 2122 [2023-02-02]. ISBN 978-0-85369-840-1. （原始内容存档于2020-05-29）. Norgestrienone is a progestogen structurally related to norethisterone that has been used as an oral contraceptive. Typical doses have been 2 mg daily with an oestrogen, and 350 micrograms daily when used alone.