阿巴诺喹

维基百科,自由的百科全书
阿巴诺喹
臨床資料
ATC碼
  • 未分配
识别信息
  • 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine
CAS号90402-40-7
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C22H25N3O4
摩尔质量395.46 g·mol−1
3D模型(JSmol英语JSmol
  • COC1=C(C=C2CN(CCC2=C1)C3=NC4=CC(=C(C=C4C(=C3)N)OC)OC)OC
  • InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24) checkY
  • Key:ANZIISNSHPKVRV-UHFFFAOYSA-N checkY

阿巴诺喹INN:abanoquil;开发代号:UK-52,046)是一种α1-肾上腺素能受体拮抗剂、抗心律失常药物。[1]一项研究显示阿巴诺喹可能可以用于治疗勃起功能障碍[2]

参考资料[编辑]

  1. ^ Tham TC, Guy S, Shanks RG, Harron DW. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. British Journal of Clinical Pharmacology. April 1992, 33 (4): 405–9. PMC 1381330可免费查阅. PMID 1349492. doi:10.1111/j.1365-2125.1992.tb04059.x. 
  2. ^ Giraldi, A.; Wyllie, M.; Wagner, G. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. International Journal of Impotence Research. 2000-03,. 12 Suppl 1 [2024-03-17]. ISSN 0955-9930. PMID 10845763. (原始内容存档于2024-03-17).