非苏拉赞

**非苏拉赞**
臨床資料
商品名（英语：Drug nomenclature）	Fexuclue
其他名稱	Abeprazan; DWP14012; DWP-14012
法律規範狀態
法律規範	Rx in South Korea, Mexico;
识别信息
	IUPAC命名法 1-[5-(2,4-Difluorophenyl)-1-(3-fluorophenyl)sulfonyl-4-methoxypyrrol-3-yl]-N-methylmethanamine; ;
CAS号	1902954-60-2
PubChem CID	122662112;
DrugBank	DB16078;
ChemSpider	68006985;
UNII	BE52S2C1QT;
ChEMBL	ChEMBL4594445;
化学信息
化学式	C19H17F3N2O3S
摩尔质量	410.41 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CNCC1=CN(C(=C1OC)C2=C(C=C(C=C2)F)F)S(=O)(=O)C3=CC=CC(=C3)F;
	InChI InChI=1S/C19H17F3N2O3S/c1-23-10-12-11-24(28(25,26)15-5-3-4-13(20)8-15)18(19(12)27-2)16-7-6-14(21)9-17(16)22/h3-9,11,23H,10H2,1-2H3; Key:OUNXGNDVWVPCOL-UHFFFAOYSA-N;

非苏拉赞（英语：Fexuprazan，商品名Fexuclue，分子式：C₁₉H₁₇F₃N₂O₃S）是一种治疗胃食道逆流病的药物，^[1]它是一种钾离子竞争性酸阻滞剂（英语：potassium-competitive acid blocker）。^[2]

它在韩国和墨西哥已获批使用。^[3]^[4]

参考文献[编辑]

^ Ramani, Azaan; Merchant, Alisha; Cash, Brooks D. Review of the clinical development of fexuprazan for gastroesophageal reflux–related disease. European Journal of Clinical Pharmacology. 2023, 79 (8): 1023–1029. PMID 37344679. S2CID 259222741. doi:10.1007/s00228-023-03521-4.
^ Kim, Gwang Ha; Choi, Myung-Gyu; Kim, Jin Il; Lee, Soo Teik; Chun, Hoon Jai; Lee, Kook Lae; Choi, Suk Chei; Jang, Jae-Young; Lee, Yong Chan; Kim, Jae Gyu; Kim, Ki Bae; Shim, Ki-Nam; Sohn, Chong Il; Kim, Sung Kook; Kim, Sang Gyun; Jang, Jin Seok; Kim, Nayoung; Jung, Hwoon-Yong; Park, Hyojin; Huh, Kyu Chan; Lee, Kwang Jae; Hong, Su Jin; Baek, Song; Han, Jin Joo; Lee, Oh Young. Efficacy and Safety of Fexuprazan in Patients with Acute or Chronic Gastritis. Gut and Liver. 2023, 17 (6): 884–893. PMC 10651377 . PMID 36789577. doi:10.5009/gnl220457.
^ 펙수클루정40밀리그램(펙수프라잔염산염). nedrug.mfds.go.kr.
^ Daewoong Pharma's GER drug gets product OK from Mexico. Korea Economic Daily. October 19, 2023 [2023-11-30]. （原始内容存档于2023-11-28）.