2,3-二氯苯甲腈

2,3-二氯苯甲腈
识别
CAS号	6574-97-6
性质
化学式	C7H3ClN
摩尔质量	136.56 g·mol−1
外观	浅黄色针状晶体
熔点	56—57 °C（329—330 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

2,3-二氯苯甲腈是一种有机化合物，化学式为C₇H₃ClN，它二氯苯甲腈的同分异构体之一。它可由2,3-二氯苯甲醛和盐酸羟胺为原料反应制得，^[2]2,3-二氯苯甲酰胺和三氯氧磷加热反应也能得到产物。^[3]在三氯化铟存在下，它可以被硼氢化钠在四氢呋喃中还原为2,3-二氯苄胺。^[4]

参考文献[编辑]

^ ^1.0 ^1.1 Rahman, Loay K. A.; Scrowston, Richard M. 7-Substituted benzo[b]thiophenes and 1,2-benzisothiazoles. Part 2. Chloro and nitro derivatives. Journal of the Chemical Society, Perkin Transactions 1 (Royal Society of Chemistry (RSC)). 1984: 385. ISSN 0300-922X. doi:10.1039/p19840000385.
^ Hongyan Lin, Ziling Zhou, Xiaopeng Ma, Qingqing Chen, Hongwei Han, Xiaoming Wang, Jinliang Qi, Yonghua Yang. One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment. RSC Advances. 2021, 11 (39): 24232–24237 [2021-12-21]. ISSN 2046-2069. doi:10.1039/D1RA03559B （英语）.
^ Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Stephen Condon, Steven W. Elmore, James F. Kerwin, Kevin B. Sippy, Karin Tietje, Michael D. Wendt, Arthur A. Hancock, Michael E. Brune, Steven A. Buckner, Irene Drizin. Structure−Activity Studies for a Novel Series of Tricyclic Substituted Hexahydrobenz[ e ]isoindole α 1A Adrenoceptor Antagonists as Potential Agents for the Symptomatic Treatment of Benign Prostatic Hyperplasia (BPH). Journal of Medicinal Chemistry. 2000-04-01, 43 (8): 1586–1603 [2021-12-21]. ISSN 0022-2623. doi:10.1021/jm990567u （英语）.
^ Jaime Z. Saavedra, Angel Resendez, Alexander Rovira, Scott Eagon, Dustin Haddenham, Bakthan Singaram. Reaction of InCl 3 with Various Reducing Agents: InCl 3 –NaBH 4 -Mediated Reduction of Aromatic and Aliphatic Nitriles to Primary Amines. The Journal of Organic Chemistry. 2012-01-06, 77 (1): 221–228 [2021-12-21]. ISSN 0022-3263. doi:10.1021/jo201809a. （原始内容存档于2021-12-21）（英语）.

[Rahman-1] 1.0 ^1.1 Rahman, Loay K. A.; Scrowston, Richard M. 7-Substituted benzo[b]thiophenes and 1,2-benzisothiazoles. Part 2. Chloro and nitro derivatives. Journal of the Chemical Society, Perkin Transactions 1 (Royal Society of Chemistry (RSC)). 1984: 385. ISSN 0300-922X. doi:10.1039/p19840000385.

[2] Hongyan Lin, Ziling Zhou, Xiaopeng Ma, Qingqing Chen, Hongwei Han, Xiaoming Wang, Jinliang Qi, Yonghua Yang. One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment. RSC Advances. 2021, 11 (39): 24232–24237 [2021-12-21]. ISSN 2046-2069. doi:10.1039/D1RA03559B （英语）.

[3] Michael D. Meyer, Robert J. Altenbach, Fatima Z. Basha, William A. Carroll, Stephen Condon, Steven W. Elmore, James F. Kerwin, Kevin B. Sippy, Karin Tietje, Michael D. Wendt, Arthur A. Hancock, Michael E. Brune, Steven A. Buckner, Irene Drizin. Structure−Activity Studies for a Novel Series of Tricyclic Substituted Hexahydrobenz[ e ]isoindole α 1A Adrenoceptor Antagonists as Potential Agents for the Symptomatic Treatment of Benign Prostatic Hyperplasia (BPH). Journal of Medicinal Chemistry. 2000-04-01, 43 (8): 1586–1603 [2021-12-21]. ISSN 0022-2623. doi:10.1021/jm990567u （英语）.

[4] Jaime Z. Saavedra, Angel Resendez, Alexander Rovira, Scott Eagon, Dustin Haddenham, Bakthan Singaram. Reaction of InCl 3 with Various Reducing Agents: InCl 3 –NaBH 4 -Mediated Reduction of Aromatic and Aliphatic Nitriles to Primary Amines. The Journal of Organic Chemistry. 2012-01-06, 77 (1): 221–228 [2021-12-21]. ISSN 0022-3263. doi:10.1021/jo201809a. （原始内容存档于2021-12-21）（英语）.

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