N,1-二甲基色胺是一種有機化合物,化學式為C12H16N2,它是二甲基色胺的同分異構體之一,為芳環氮和氨基氮上的氫各被一個甲基取代的產物。它可由N-叔丁氧羰基-N,1-二甲基色胺在三氟乙酸的二氯甲烷溶液中脫Boc保護得到[2],或由相應的酰胺還原得到[3]。它的氨基氮上可以進一步甲基化,得到季銨鹽[2]。
參考文獻[編輯]
- ^ Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2021 ACD/Labs). Retrieved from SciFinder. [2021-07-22].
- ^ 2.0 2.1 Pérez, Edwin G.; Cassels, Bruce K.; Eibl, Christoph; Gündisch, Daniela. Synthesis and evaluation of N1-alkylindole-3-ylalkylammonium compounds as nicotinic acetylcholine receptor ligands. Bioorganic & Medicinal Chemistry. 2012-06, 20 (12): 3719–3727. doi:10.1016/j.bmc.2012.04.050 (英語).
- ^ Jamison, Christopher R.; Badillo, Joseph J.; Lipshultz, Jeffrey M.; Comito, Robert J.; MacMillan, David W. C. Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products. Nature Chemistry. 2017-12, 9 (12): 1165–1169 [2022-03-23]. ISSN 1755-4330. doi:10.1038/nchem.2825. (原始內容存檔於2022-03-13) (英語).