1-Boc-4-AP

**1-Boc-4-AP**
法律規範狀態
法律規範	美：List 1;
識別資訊
	IUPAC命名法 tert-butyl 4-anilinopiperidine-1-carboxylate; ;
CAS號	125541-22-2
PubChem CID	1491502;
UNII	5PB6P54SRS;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID90363439 ;
化學資訊
化學式	C16H24N2O2
摩爾質量	276.38 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES CC(C)(C)OC(=O)N1CCC(CC1)NC2=CC=CC=C2;
	InChI InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3; Key:HTIWISWAPVQGMI-UHFFFAOYSA-N;

1-Boc-4-AP（4-苯胺基哌啶-1-甲酸叔丁酯）是用於合成芬太尼及其類似物的中間體，是4-苯胺基哌啶的N-保護衍生物。它於2022年被美國DEA列入I類監控化學品，並在其他多個司法管轄區受到管制。持有、銷售或進口在世界大部分地區都受到嚴格監管。^[1]儘管它的藥理活性尚不清楚，它在其它狡詐家藥物作為雜質中被檢測出。^[2]

參考文獻[編輯]

^ Specific Listing for 1-boc-4-AP, a Currently Controlled List I Chemical.. Federal Register, 87 FR 67550-67553. 9 November 2022 [2023-12-02]. （原始內容存檔於2023-11-05）.
^ May C, Downey C, Power JD, Kavanagh PV. An unusual detection of tert-butyl-4-anilinopiperidine-1-carboxylate in seizures of falsified 'Xanax' tablets and in items in a suspected heroin seizure submitted by Irish law enforcement. Drug Testing and Analysis. September 2020, 12 (9): 1387–1392. PMID 32567251. S2CID 219974817. doi:10.1002/dta.2884.

[1] Specific Listing for 1-boc-4-AP, a Currently Controlled List I Chemical.. Federal Register, 87 FR 67550-67553. 9 November 2022 [2023-12-02]. （原始內容存檔於2023-11-05）.

[pmid32567251-2] May C, Downey C, Power JD, Kavanagh PV. An unusual detection of tert-butyl-4-anilinopiperidine-1-carboxylate in seizures of falsified 'Xanax' tablets and in items in a suspected heroin seizure submitted by Irish law enforcement. Drug Testing and Analysis. September 2020, 12 (9): 1387–1392. PMID 32567251. S2CID 219974817. doi:10.1002/dta.2884.

[1]

[2]